Antifungal Therapy
For fungal keratitis and other serious ocular infections, we prepare antifungal ophthalmic solutions not available commercially, including:
- Amphotericin B ophthalmic solution
- Voriconazole 1% ophthalmic solution
Ophthalmology
Ophthalmology
A Sterile Compounding Portfolio Built for Specialty Eye Care
The eye is one of the most sensitive organs in the body — and one of the most demanding when it comes to medication tolerability. Commercially available eye drops contain preservatives, stabilizers, and pH buffers that work for most patients most of the time. But for patients with chronic eye conditions, post-surgical eyes, or significant sensitivities, those additives can cause irritation, inflammation, and treatment non-compliance.
Compounded ophthalmic medications offer a meaningful alternative: formulations built precisely to what the eye needs, without what it doesn’t.
Voshell’s Pharmacy maintains a comprehensive sterile ophthalmic compounding portfolio spanning 9 disease-state categories — covering every major specialty service from corneal disease and retina to glaucoma, pediatric ophthalmology, and ocular oncology. Our formulations are prepared under USP <797> sterile compounding standards in an ISO 5 cleanroom.
The Case for Preservative-Free Formulations
Preservatives like benzalkonium chloride (BAK) are standard in commercial eye drops — but they are also a recognized source of ocular surface toxicity in patients who use medicated drops multiple times daily over months or years.
Preservative-free compounding can be especially important for:
- Dry eye disease
- Glaucoma patients requiring chronic therapy
- Post-operative inflammation management
- Pediatric ophthalmology
- Patients with ocular surface disease or medication sensitivity
Conditions
Conditions We Support
Cornea and External Disease
Dry Eye Disease
Our dry eye portfolio includes immunomodulatory and mucolytic preparations in multiple vehicles, formulated to match the clinical and tolerability needs of each patient:
- Cyclosporine 0.1%–3% ophthalmic solution
- Cyclosporine/Tacrolimus combination solution
- Acetylcysteine 5%–10% ophthalmic solution
Corneal and Band Keratopathy
Edetate disodium (EDTA) ophthalmic solutions in multiple concentrations are available for chelation therapy in calcium-related corneal disease.
Ocular Infection
Broad-spectrum and targeted antibiotic formulations for bacterial keratitis, post-surgical prophylaxis, and endophthalmitis management, including:
- Tobramycin/Vancomycin combination
- Gentamicin ophthalmic solution
- Vancomycin ophthalmic solution and injection
- Amikacin 0.3%
- Cefazolin 50 mg/mL
- Ceftazidime 50 mg/mL
- Tobramycin/Vancomycin/Dexamethasone combination solution
Inflammation
Preservative-free corticosteroid solutions for ocular inflammation across cornea, retina, and comprehensive eye care settings:
- Dexamethasone sodium phosphate 0.1%
- Prednisolone sodium phosphate 1%
- Methylprednisolone sodium succinate 1%
Glaucoma Service
Preservative-free and specialty glaucoma formulations for patients on long-term intraocular pressure management:
- Timolol 0.5% ophthalmic solution
- Pilocarpine 0.01%–0.25% ophthalmic solution
- Apraclonidine 0.125% ophthalmic solution
Pediatric Ophthalmology and Strabismus
Low-dose atropine ophthalmic solution (0.01%–0.05%) for pediatric myopia control — one of the most clinically studied compounded preparations in ophthalmology today. Dosing range allows prescribers to titrate to each child’s response.
Ocular Surface Neoplasia
5-Fluorouracil 1% ophthalmic solution for ocular surface squamous neoplasia (OSSN) — a compounding-only formulation with no commercial equivalent at this concentration.
Specialty and Immunomodulatory
Advanced formulations for complex ocular conditions across multiple specialties:
- Tacrolimus 0.02%–1% ophthalmic oil solution: immunomodulatory; vernal keratoconjunctivitis
- Testosterone 0.05% ophthalmic oil solution: meibomian gland dysfunction and androgen-deficiency dry eye
- Insulin 25 U/mL ophthalmic solution: neurotrophic keratopathy; corneal healing support
- Glutathione 1.25% / Ascorbic Acid 1.25% ophthalmic solution: antioxidant therapy for oxidative stress corneal disease
- DMSO 6.25% ophthalmic solution: penetration enhancer for specialty applications
Delivery Forms Available
Our compounding team can prepare ophthalmic medications in a range of delivery forms to match the clinical need:
- Eye drops (solutions): the most common delivery form for both topical and anti-infective therapy
- Suspensions: for medications that require even distribution of fine particles
- Ophthalmic ointments and gels: for overnight use, dry eye therapy, or conditions requiring prolonged contact time
- Intravitreal preparations: sterile intraocular formulations prepared under strict aseptic conditions (physician-administered)
Compounding
Our Sterile Compounding Standards
All ophthalmic compounds prepared at Voshell’s Pharmacy meet USP <797> sterile compounding standards. As the first accredited sterile compounding pharmacy in Baltimore, we bring a long history of precision and accountability to every ophthalmic preparation.
if a compounded formulation may be right for you
Compliance Note
Compounded ophthalmic medications are prepared based on individual prescriptions from licensed prescribers. All sterile preparations are compounded in compliance with USP <797> standards. Compounded medications are not FDA-approved drug products. They may not be appropriate for all patients or all clinical situations.